DelveInsight’s, “Recurrent Glioblastoma Pipeline Insight, 2022,” report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Recurrent Glioblastoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Key takeaways from the Recurrent Glioblastoma Pipeline Report
Recent Developmental Activities in the Recurrent Glioblastoma Pipeline
Request a sample and discover more about the Recurrent Glioblastoma pipeline report offerings @ Recurrent Glioblastoma Pipeline Outlook Report
Recurrent Glioblastoma Overview
Recurrent glioblastoma is a possibility that oncologists – and patients – must keep in mind during and after an initial course of treatment. Because it can be difficult to completely remove a tumor during surgery, there is always a possibility that the cancer might come back after a period of remission. As a result, survivors are typically scheduled for follow-up appointments and surveillance imaging every few months after the completion of their initial treatments. Glioblastoma can come back anywhere in the brain or spinal cord. However, most recurrences are found near the site of the original tumor. Without treatment, the median survival with glioblastoma is only a few months, but even with treatment, survival is frequently only around one year.
Recurrent Glioblastoma Pipeline Report
In the Recurrent Glioblastoma pipeline report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Recurrent Glioblastoma collaborations, licensing, mergers and acquisition, funding, designations and other product related detail.
Recurrent Glioblastoma Emerging Drugs Profile
ASC40: Ascletis
ASC40 is an oral, selective inhibitor of fatty acid synthase (FASN), a key enzyme which regulates de novo lipogenesis (DNL). ASC40 inhibits energy supply and disturbs membrane phospholipid composition of tumor cells by blocking de novo lipogenesis. In January 2022, Ascletis Pharma Inc. announced the dosing of the first patient in the Phase III registration clinical trial of ASC40 combined with bevacizumab for treatment of recurrent glioblastoma (rGBM). The Phase II study, completed in the U.S., in patients with rGBM has shown that the objective response rate (ORR) for ASC40 plus Bevacizumab treatment was 65% including a complete response (CR) of 20% and a partial response (PR) of 45%.
GX-I7: Genexine
GX-I7 is a long-acting human IL-7 which is essential for homeostatic T cell proliferation and improves lymphopenia, typically induced by chemotherapy or radiation therapy. The safety has been proved via phase I clinical trial in healthy volunteers and phase Ib and Ib/2 Clinical trials are being conducted to evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics and efficacy.
Olinvacimab: PharmAbcine
Olinvacimab is an anti-angiogenic antibody that neutralizes the VEGF/VEGFR2 pathway, thus inhibiting tumor growth and metastasis. It blocks the binding of all VEGFR ligands such as VEGF-A, VEGF-C and VEGF-D to VEGFR2. To gain nutrients and oxygen needed for growth, tumor cells release these VEGF ligands which promote angiogenesis (a formation of new blood vessels) that will enhance tumor blood supply. Binding of olinvacimab to VEGFR2 will result in the inhibition of VEGF-mediated tumor angiogenesis.
Recurrent Glioblastoma Pipeline Assessment
There are approx. 50+ key companies which are developing the therapies for Recurrent Glioblastoma. The companies which have their Recurrent Glioblastoma drug candidates in the most advanced stage, i.e. phase III include, Ascletis.
Find out more about the disease and recent cancer research developments @ Recurrent Glioblastoma Ongoing Clinical Trials Analysis
Recurrent Glioblastoma Pipeline Therapeutics Analysis
The Recurrent Glioblastoma Pipeline report proffers an integral view of the Recurrent Glioblastoma emerging novel therapies segmented by Stage, Product Type, Molecule Type, Mechanism of Action and Route of Administration.
Scope of the Recurrent Glioblastoma Pipeline Report
Table of Content
Key Questions
Current Treatment Scenario and Emerging Therapies:
For further information on the Recurrent Glioblastoma Pipeline therapeutics, reach out to Recurrent Glioblastoma Treatment Landscape
Media ContactCompany Name: DelveInsight LLPContact Person: Yash BhardwajEmail: Send EmailPhone: 09193216187Address:304 S. Jones Blvd #2432, City: Las VegasState: United StatesCountry: IndiaWebsite: https://www.delveinsight.com/